A nutrient-wide association study for risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition and the Netherlands Cohort Study. ...

Funder: Centre International de Recherche sur le Cancer; doi: http://dx.doi.org/10.13039/100008700 ... : PURPOSE: The evidence from the literature regarding the association of dietary factors and risk of prostate cancer is inconclusive. METHODS: A nutrient-wide association study was conducted to systematically and comprehensively evaluate the associations between 92 foods or nutrients and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC). Cox proportional hazard regression models adjusted for total energy intake, smoking status, body mass index,... Mehr ...

Verfasser: Papadimitriou, Nikos
Muller, David
Van Den Brandt, Piet A
Geybels, Milan
Patel, Chirag J
Gunter, Marc J
Lopez, David S
Key, Timothy J
Perez-Cornago, Aurora
Ferrari, Pietro
Vineis, Paolo
Weiderpass, Elisabete
Boeing, Heiner
Agudo, Antonio
Sánchez, María-José
Overvad, Kim
Kühn, Tilman
Fortner, Renee T
Palli, Domenico
Drake, Isabel
Bjartell, Anders
Santiuste, Carmen
Bueno-De-Mesquita, Bas H
Krogh, Vittorio
Tjønneland, Anne
Lauritzen, Dorthe Furstrand
Gurrea, Aurelio Barricarte
Quirós, José Ramón
Stattin, Pär
Trichopoulou, Antonia
Martimianaki, Georgia
Karakatsani, Anna
Thysell, Elin
Johansson, Ingegerd
Ricceri, Fulvio
Tumino, Rosario
Larrañaga, Nerea
Khaw, Kay Tee
Riboli, Elio
Tzoulaki, Ioanna
Tsilidis, Konstantinos K
Dokumenttyp: Scholarlyarticle
Erscheinungsdatum: 2020
Verlag/Hrsg.: Springer Science and Business Media LLC
Schlagwörter: Cohort study / Diet / Epidemiology / Nutrition / Prostate cancer / Cohort Studies / Europe / Genome-Wide Association Study / Humans / Male / Netherlands / Nutrients / Prospective Studies / Prostatic Neoplasms / Risk Factors
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-29160461
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://dx.doi.org/10.17863/cam.59699

Funder: Centre International de Recherche sur le Cancer; doi: http://dx.doi.org/10.13039/100008700 ... : PURPOSE: The evidence from the literature regarding the association of dietary factors and risk of prostate cancer is inconclusive. METHODS: A nutrient-wide association study was conducted to systematically and comprehensively evaluate the associations between 92 foods or nutrients and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC). Cox proportional hazard regression models adjusted for total energy intake, smoking status, body mass index, physical activity, diabetes and education were used to estimate hazard ratios and 95% confidence intervals for standardized dietary intakes. As in genome-wide association studies, correction for multiple comparisons was applied using the false discovery rate (FDR < 5%) method and suggested results were replicated in an independent cohort, the Netherlands Cohort Study (NLCS). RESULTS: A total of 5916 and 3842 incident cases of prostate cancer were diagnosed during a mean follow-up of 14 and 20 years in EPIC and NLCS, ...