Childhood and adolescent energy restriction and subsequent colorectal cancer risk: results from the Netherlands Cohort Study

International audience ; Background: Energy restriction during childhood and adolescence is suggested to lower colorectal cancer (CRC) risk. We investigated this in the Netherlands Cohort Study. Methods: Information on diet and other risk factors was collected by a baseline questionnaire in 1986 when cohort members were 55-69 years of age (n=120,852). Three indicators of early life exposure to energy restriction were assessed: father's employment status during the Economic Depression (1932-40), and place of residence during World War 2 years (1940-44) and the 'Hunger Winter' (1944-45); a sever... Mehr ...