Prevalence and molecular mechanism of macrolide resistance in β-haemolytic streptococci in The Netherlands

International audience ; The prevalence of resistance to erythromycin and clindamycin as well as the presence of the resistance genes (A), (E), (A) and (B) were determined in 1076 consecutive isolates of β-haemolytic streptococci of Lancefield groups A (=219), B (=562),C (=58) and G (=237) collected during 2005 and 2006. The prevalence of macrolide resistance was highest in group C streptococci (6.9%), followed by group B (5.3%), group G (4.6%) and group A (1.4%). Eighty-eight percent of resistance was mediated by (A) and (B) genes. Macrolide resistance in β-haemolytic streptococci in The Neth... Mehr ...