Transmitted drug resistance, selection of resistance mutations and moderate antiretroviral efficacy in HIV-2: Analysis of the HIV-2 Belgium and Luxembourg database
Background: Guidelines established for the treatment of HIV-1 infection and genotype interpretation do not apply for HIV-2. Data about antiretroviral ( ARV) drug efficacy and resistance mutations is scarce. Methods: Clinical data about HIV-2 infected patients in Belgium and Luxembourg were collected and the effect of ARV therapy on plasma viral load and CD4 counts were analysed. Viral RNA encoding for protease ( PR) and reverse transcriptase ( RT) from ARV-naive and treated patients were sequenced. Results: Sixty-five HIV-2 infected patients were included in this cohort. Twenty patients were t... Mehr ...
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Dokumenttyp: | journalarticle |
Erscheinungsdatum: | 2008 |
Verlag/Hrsg.: |
BIOMED CENTRAL LTD
CURRENT SCIENCE GROUP MIDDLESEX HOUSE 34-42 CLEVELAND ST LONDON W1T 4LB ENGLAND |
Schlagwörter: | Medicine and Health Sciences / INFECTED-PATIENTS / NATURAL POLYMORPHISMS / PROTEASE INHIBITORS / HIV-2-INFECTED PATIENTS / REVERSE-TRANSCRIPTASE / HUMAN-IMMUNODEFICIENCY-VIRUS / PLASMA VIRAL LOAD / TYPE-2 INFECTION / CELL DECLINE / COTE-DIVOIRE |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-29107553 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://biblio.ugent.be/publication/603347 |