In the past decades, the low-lying region Flanders (Belgium) has fall victim to numerous flood events, causing substantial damage to buildings and infrastructure. In response to this, the Flemish government proposed a new approach which considers the level of risk as a way for safety measurement. Using geographical information systems, this evolution has lead to a comprehensive risk methodology, and more recently to the development of a flood risk assessment tool called LATIS. By estimating the potential damage and the number of casualties during a flood event, LATIS offers the possibility to perform risk analysis in a fast and effective way. This paper presents a brief overview of the currently used methodology for flood risk management in Flanders and its implementation in the LATIS tool. The usefulness of this new tool is demonstrated by a sequence of risk calculations, performed in the framework of climate change impacts on flood risk in Flanders.