Even though road transport is an essential part of freight distribution, there is a lack of customized routing networks to convey freight over the road. The present paper addresses this deficit by proposing general principles to elaborate a regional freight route network in Flanders. However, assigning regional freight traffic to a particular road network involves complex trade-offs between multiple interests, such as corporate accessibility, communal livability, additional network links and available space. The paper recommends the multi-actor multi-criteria assessment tool (MAMCA) to incorporate stakeholder objectives in the evaluation of possible freight network scenarios. The tool is applied for the specific case of Anzegem, a road village amid regional freight attraction poles that suffers particularly from heavy freight flows. The impact of four alternative ring ways is assessed according to the interests of the involved parties and compared to the reference scenario. Results show that transport companies advocate supra-local accessibility, while governmental and citizen stakeholders value traffic safety and livability. Since the reference scenario does not comply with these critical stakeholder objectives, an alternate scenario is proposed. As such, MAMCA applications assist policy-makers in building consensus among multiple actors in the realization of transportation projects.