Malaria anticircumsporozoite antibodies in dutch soldiers returning from sub‐saharan africa

One hundred and twenty‐five Dutch servicemen returning from central Africa after a short deployment were enrolled in a study aimed at assessing the effectiveness of malaria prevention measures. None of the persons developed an episode of clinically overt malaria during or after deployment, and no antibodies against blood stages of Plasmodium falciparum could be found. However, antibodies against the circumsporozoite protein (CS) of P. falciparum were demonstrable in 14 persons (11.2% of the study population) by an ELISA test using the recombinant CS‐antigen R32tet 32, while one person only was... Mehr ...