The Dutch Protocol: Coming of Age:Treatment trajectories and long-term bone development in transgender adolescents

The safety and efficacy of the Dutch Protocol is highly debated. Among the concerns regarding long-term safety of puberty suppression is a potential harmful effect on BMD accrual. Furthermore, the recent, unexplained, rise in predominantly AFAB referrals poses the question whether this particular group is different to former individuals. This could apply to personal traits, such as age and co-occurrence of psychological conditions, as well as characteristics of gender dysphoria, such as age at onset. The objective of this thesis was to shed light on outcomes in children and adolescents referre... Mehr ...