Direct-Acting Antiviral Treatment for Hepatitis C Genotypes Uncommon in High-Income Countries: A Dutch Nationwide Cohort Study

Background: The majority of hepatitis C virus (HCV) infections are found in low- and middle-income countries, which harbor many region-specific HCV subtypes. Nevertheless, direct-acting antiviral (DAA) trials have almost exclusively been conducted in high-income countries, where mainly epidemically spread HCV subtypes are present. Recently, several studies have demonstrated suboptimal DAA efficacy for certain nonepidemic subtypes, which could hamper global HCV elimination. Therefore, we aimed to evaluate DAA efficacy in patients treated for a nonepidemic HCV genotype infection in the Netherlan... Mehr ...

Verfasser: Isfordink, Cas J.
Van De Laar, Thijs J.W.
Rebers, Sjoerd P.H.
Wessels, Els
Molenkamp, Richard
Knoester, Marjolein
Baak, Bert C.
Van Nieuwkoop, Cees
Van Hoek, Bart
Brakenhoff, Sylvia M.
Blokzijl, Hans
Arends, Joop E.
Van Der Valk, Marc
Schinkel, Janke
Dokumenttyp: Artikel
Erscheinungsdatum: 2021
Schlagwörter: Africa / Asia / elimination / global health / unusual subtypes / Clinical Neurology / Oncology / Journal Article
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-29040280
Datenquelle: BASE; Originalkatalog
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Link(s) : https://dspace.library.uu.nl/handle/1874/442816