Analysis of simulated outbreaks with fixed model parameters in the MCMC runs, while varying the number of introductions and coalescent rate in the history host.

The model parameters are fixed at the simulation values. (A) The mean estimated median number of introductions. The black line indicates the simulated number of introductions. (B) Percentage of correctly identified infectors. The grey bar indicates cases for which the true infector has the highest posterior weight. The transparent bar indicates cases for which the true infector is contained in the smallest set of candidate infectors with at least 95% of the posterior weight. (C) Classification of the incorrectly identified infectors in the maximum credibility tree. The grey bars indicate the c... Mehr ...

Verfasser: Bastiaan R. Van der Roest
Martin C. J. Bootsma
Egil A. J. Fischer
Don Klinkenberg
Mirjam E. E. Kretzschmar
Dokumenttyp: Image
Erscheinungsdatum: 2023
Schlagwörter: Medicine / Biotechnology / Evolutionary Biology / Ecology / Cancer / Infectious Diseases / Computational Biology / Biological Sciences not elsewhere classified / Mathematical Sciences not elsewhere classified / Information Systems not elsewhere classified / determine risk factors / aid infection control / multiple phylogenetic clusters / method correctly identifies / bayesian inference method / infectious disease outbreaks / div >< p / dutch mink farms / introduced multiple times / estimate transmission trees / genome sequencing data / infectious disease / genome sequencing / mink farms / transmission trees / multiple introductions / 63 farms / 13 farms / transmission routes / transmission events / single introduction / priori split / phybreak </ / observed cases / new feature / host dynamics / existing models / epidemiological data / complex class / always true / additional feature / accuracy depending
Sprache: unknown
Permalink: https://search.fid-benelux.de/Record/base-29034404
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://doi.org/10.1371/journal.pcbi.1010928.s006

The model parameters are fixed at the simulation values. (A) The mean estimated median number of introductions. The black line indicates the simulated number of introductions. (B) Percentage of correctly identified infectors. The grey bar indicates cases for which the true infector has the highest posterior weight. The transparent bar indicates cases for which the true infector is contained in the smallest set of candidate infectors with at least 95% of the posterior weight. (C) Classification of the incorrectly identified infectors in the maximum credibility tree. The grey bars indicate the correctly identified infectors. S: single transmission cluster involved, M: multiple transmission clusters involved. C→C: simulated and inferred infectors are cases, H→C: simulated infector was history host, inferred infector is case, C→H: simulated infector was case, inferred infector is history host. (TIF)