Penetrance and Prognosis of MYH7 Variant-Associated Cardiomyopathies:Results From a Dutch Multicenter Cohort Study
BACKGROUND: MYH7 variants cause hypertrophic cardiomyopathy (HCM), noncompaction cardiomyopathy (NCCM), and dilated cardiomyopathy (DCM). Screening of relatives of patients with genetic cardiomyopathy is recommended from 10 to 12 years of age onward, irrespective of the affected gene. OBJECTIVES: This study sought to study the penetrance and prognosis of MYH7 variant-associated cardiomyopathies. METHODS: In this multicenter cohort study, penetrance and major cardiomyopathy-related events (MCEs) were assessed in carriers of (likely) pathogenic MYH7 variants by using Kaplan-Meier curves and log-... Mehr ...
| Verfasser: |
Jansen, Mark
de Brouwer, Remco
Hassanzada, Fahima
Schoemaker, Angela E
Schmidt, Amand F
Kooijman-Reumerman, Maria D
Bracun, Valentina
Slieker, Martijn G
Dooijes, Dennis
Vermeer, Alexa M C
Wilde, Arthur A M
Amin, Ahmad S
Lekanne Deprez, Ronald H
Herkert, Johanna C
Christiaans, Imke
de Boer, Rudolf A
Jongbloed, Jan D H
van Tintelen, J Peter
Asselbergs, Folkert W
Baas, Annette F |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2024 |
| Reihe/Periodikum: |
Jansen , M , de Brouwer , R , Hassanzada , F , Schoemaker , A E , Schmidt , A F , Kooijman-Reumerman , M D , Bracun , V , Slieker , M G , Dooijes , D , Vermeer , A M C , Wilde , A A M , Amin , A S , Lekanne Deprez , R H , Herkert , J C , Christiaans , I , de Boer , R A , Jongbloed , J D H , van Tintelen , J P , Asselbergs , F W & Baas , A F 2024 , ' Penetrance and Prognosis of MYH7 Variant-Associated Cardiomyopathies : Results From a Dutch Multicenter Cohort Study ' , JACC: Heart Failure , vol. 12 , no. 1 , pp. 134-147 . https://doi.org/10.1016/j.jchf.2023.07.007 |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-29028814 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://hdl.handle.net/11370/c44d2fe0-9ac5-43d3-afff-b663348a73db |
