Differences in Trial and Real-world Populations in the Dutch Castration-resistant Prostate Cancer Registry

Background: Trials in castration-resistant prostate cancer (CRPC) treatment have shown improved outcomes, including survival. However, as trial populations are selected, results may not be representative for the real-world population. The aim of this study was to assess the differences between patients treated in a clinical trial versus standard care during the course of CRPC in a real-world CRPC population. Design, setting, and participants: Castration-resistant Prostate Cancer Registry is a population-based, observational, retrospective registry. CRPC patients from 20 hospitals in the Nether... Mehr ...

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Verfasser: Westgeest, Hans M.
Uyl-de Groot, Carin A.
van Moorselaar, Reindert J.A.
de Wit, Ronald
van den Bergh, Alphonsus C.M.
Coenen, Jules L.L.M.
Beerlage, Harrie P.
Hendriks, Mathijs P.
Bos, Monique M.E.M.
van den Berg, Pieter
van de Wouw, Agnes J.
Spermon, Roan
Boerma, Michiel O.
Geenen, Maud M.
Tick, Lidwine W.
Polee, Marco B.
Bloemendal, Haiko J.
Cordia, Igor
Peters, Frank P.J.
de Vos, Aad I.
van den Bosch, Joan
van den Eertwegh, Alphonsus J.M.
Gerritsen, Winald R.
Dokumenttyp: Artikel
Erscheinungsdatum: 2018
Reihe/Periodikum: Westgeest , H M , Uyl-de Groot , C A , van Moorselaar , R J A , de Wit , R , van den Bergh , A C M , Coenen , J L L M , Beerlage , H P , Hendriks , M P , Bos , M M E M , van den Berg , P , van de Wouw , A J , Spermon , R , Boerma , M O , Geenen , M M , Tick , L W , Polee , M B , Bloemendal , H J , Cordia , I , Peters , F P J , de Vos , A I , van den Bosch , J , van den Eertwegh , A J M & Gerritsen , W R 2018 , ' Differences in Trial and Real-world Populations in the Dutch Castration-resistant Prostate Cancer Registry ' , European Urology Focus , vol. 4 , no. 5 , pp. 694-701 . https://doi.org/10.1016/j.euf.2016.09.008
Schlagwörter: Castration-resistant prostate cancer / Docetaxel / Outcomes research / Population based / Real-world outcomes / Registry / Registry of outcomes / Treatment / Trial population
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-29028762
Datenquelle: BASE; Originalkatalog
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Link(s) : https://hdl.handle.net/11370/be52bada-2c9e-466c-a25c-3aea162bd355