OBJECTIVE: Clinicians face difficulty in when and in what order to position biologics and JAK inhibitors in anti-TNF refractory ulcerative colitis (UC) patients. We aimed to compare the effectiveness and safety of vedolizumab and tofacitinib in anti-TNF exposed UC patients in our prospective nationwide Initiative on Crohn and Colitis (ICC) Registry. METHODS: UC patients who failed anti-TNF treatment and initiated vedolizumab or tofacitinib treatment, were identified in the ICC Registry in the Netherlands. We selected patients with both clinical as well as biochemical or endoscopic disease acti... Mehr ...
| Verfasser: |
Straatmijer, Tessa
Biemans, Vince Bc
Visschedijk, Marijn
Hoentjen, Frank
de Vries, Annemarie
van Bodegraven, Adriaan A
Bodelier, Alexander
de Boer, Nanne K H
Dijkstra, Gerard
Festen, Noortje
Horjus, Carmen
Jansen, Jeroen M
Jharap, Bindia
Mares, Wout
van Schaik, Fiona Dm
Ponsioen, Cyriel
Romkens, Tessa
Srivastava, Nidhi
van der Voorn, Michael Mpja
West, Rachel
van der Woude, Janneke
Wolvers, Marije D J
Pierik, Marieke
van der Meulen-de Jong, Andrea E
Duijvestein, Marjolijn |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2023 |
| Reihe/Periodikum: |
Initiative on Crohn and Colitis , Straatmijer , T , Biemans , V B , Visschedijk , M , Hoentjen , F , de Vries , A , van Bodegraven , A A , Bodelier , A , de Boer , N K H , Dijkstra , G , Festen , N , Horjus , C , Jansen , J M , Jharap , B , Mares , W , van Schaik , F D , Ponsioen , C , Romkens , T , Srivastava , N , van der Voorn , M M , West , R , van der Woude , J , Wolvers , M D J , Pierik , M , van der Meulen-de Jong , A E & Duijvestein , M 2023 , ' Superior effectiveness of tofacitinib compared to vedolizumab in anti-TNF experienced ulcerative colitis patients : a nationwide Dutch Registry study ' , Clinical Gastroenterology and Hepatology , vol. 21 , no. 1 , pp. 182-191.e2 . https://doi.org/10.1016/j.cgh.2022.04.038 |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-29027756 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://hdl.handle.net/11370/4d7e144b-6332-47f9-9cee-542a2092238d |
