Temporal Ordering of Biomarkers in Dutch-Type Hereditary Cerebral Amyloid Angiopathy

BACKGROUND: The temporal ordering of biomarkers for cerebral amyloid angiopathy (CAA) is important for their use in trials and for the understanding of the pathological cascade of CAA. We investigated the presence and abnormality of the most common biomarkers in the largest (pre)symptomatic Dutch-Type hereditary CAA (D-CAA) cohort to date. METHODS: We included cross-sectional data from participants with (pre)symptomatic D-CAA and controls without CAA. We investigated CAA-related cerebral small vessel disease markers on 3T-MRI, cerebrovascular reactivity with functional 7T-MRI (fMRI) and amyloi... Mehr ...

Verfasser: Koemans, Emma A.
Rasing, Ingeborg
Voigt, Sabine
Van Harten, Thijs W.
Van Der Zwet, Reinier G.J.
Kaushik, Kanishk
Schipper, Manon R.
Van Der Weerd, Nelleke
Van Zwet, Erik W.
Van Etten, Ellis S.
Van Osch, Matthias J.P.
Kuiperij, Bea
Verbeek, Marcel M.
Terwindt, Gisela M.
Greenberg, Steven M.
Van Walderveen, Marianne A.A.
Wermer, Marieke J.H.
Dokumenttyp: Artikel
Erscheinungsdatum: 2024
Reihe/Periodikum: Koemans , E A , Rasing , I , Voigt , S , Van Harten , T W , Van Der Zwet , R G J , Kaushik , K , Schipper , M R , Van Der Weerd , N , Van Zwet , E W , Van Etten , E S , Van Osch , M J P , Kuiperij , B , Verbeek , M M , Terwindt , G M , Greenberg , S M , Van Walderveen , M A A & Wermer , M J H 2024 , ' Temporal Ordering of Biomarkers in Dutch-Type Hereditary Cerebral Amyloid Angiopathy ' , Stroke , vol. 55 , no. 4 , pp. 954-962 . https://doi.org/10.1161/STROKEAHA.123.044688
Schlagwörter: arteries / biomarkers / cerebral hemorrhage / magnetic resonance imaging / stroke
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-29027718
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://hdl.handle.net/11370/482ce299-481b-4c84-9a3e-eaef0e128272