Third-line Life-prolonging Drug Treatment in a Real-world Metastatic Castration-resistant Prostate Cancer Population:Results from the Dutch Castration-resistant Prostate Cancer Registry

Background: Evidence concerning third-line life-prolonging drugs (LPDs) in the treat-ment of metastatic castration-resistant prostate cancer (mCRPC) patients is incomplete. Objective: To evaluate third-line LPD outcomes in a real-world cohort of mCRPC patients, identify variables associated with overall survival (OS), and establish a prog-nostic model. Design, setting, and participants: Patients with mCRPC who were progressive on second-line LPD before July 1, 2017 were retrospectively identified from the Dutch Castration-resistant Prostate Cancer Registry (CAPRI) and followed until December 3... Mehr ...

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Verfasser: Notohardjo, Jessica C. L.
Kuppen, Malou C. P.
Westgeest, Hans M.
van Moorselaar, Reindert J. A.
Mehra, Niven
Coenen, Jules L. L. M.
van Oort, Inge M.
de Vos, Aad
Vervenne, Walter L.
van den Bergh, Alphons C. M.
Aben, Katja K. H.
Somford, Diederik M.
Bergman, Andries M.
Uyl-de Groot, Carin A.
Gerritsen, Winald R.
van den Eertwegh, Alfons J. M.
Dokumenttyp: Artikel
Erscheinungsdatum: 2021
Reihe/Periodikum: Notohardjo , J C L , Kuppen , M C P , Westgeest , H M , van Moorselaar , R J A , Mehra , N , Coenen , J L L M , van Oort , I M , de Vos , A , Vervenne , W L , van den Bergh , A C M , Aben , K K H , Somford , D M , Bergman , A M , Uyl-de Groot , C A , Gerritsen , W R & van den Eertwegh , A J M 2021 , ' Third-line Life-prolonging Drug Treatment in a Real-world Metastatic Castration-resistant Prostate Cancer Population : Results from the Dutch Castration-resistant Prostate Cancer Registry ' , European Urology Focus , vol. 7 , no. 4 , pp. 788-796 . https://doi.org/10.1016/j.euf.2020.03.009
Schlagwörter: Life-prolonging drug / Real-world outcomes / Third line / Castration-resistant prostate cancer / ABIRATERONE ACETATE / ANTITUMOR-ACTIVITY / PROGNOSTIC MODEL / DOCETAXEL / ENZALUTAMIDE / SURVIVAL / CHEMOTHERAPY / MITOXANTRONE / CABAZITAXEL / PREDNISONE
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-29027360
Datenquelle: BASE; Originalkatalog
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Link(s) : https://hdl.handle.net/11370/271f8cdc-567a-4261-a2e6-6bb7d36cae23