Plasmid diversity among genetically related Klebsiella pneumoniae bla KPC-2 and bla KPC-3 isolates collected in the Dutch national surveillance

Carbapenemase-producing Klebsiella pneumoniae emerged as a nosocomial pathogen causing morbidity and mortality in patients. For infection prevention it is important to track the spread of K. pneumoniae and its plasmids between patients. Therefore, the major aim was to recapitulate the contents and diversity of the plasmids of genetically related K. pneumoniae strains harboring the beta-lactamase gene blaKPC-2 or blaKPC-3 to determine their dissemination in the Netherlands and the former Dutch Caribbean islands from 2014 to 2019. Next-generation sequencing was combined with long-read third-gene... Mehr ...

Verfasser: Hendrickx, Antoni P.A.
Landman, Fabian
de Haan, Angela
Borst, Dyogo
Witteveen, Sandra
van Santen-Verheuvel, Marga G.
van der Heide, Han G.J.
Schouls, Leo M.
Halaby, T.
Steingrover, R.
Cohen Stuart, J. W.T.
Melles, D. C.
van Dijk, K.
Spijkerman, I. J.B.
Notermans, D. W.
Oudbier, J. H.
van Ogtrop, M. L.
van Dam, A.
den Reijer, M.
Kluytmans, J. A.J.W.
van der Linden, M. P.M.
Mattsson, E. E.
van der Vusse, M.
de Jong, E.
Maijer-Reuwer, A.
van Trijp, M.
van Griethuysen, A. J.
Ott, A.
Bathoorn, E.
Sinnige, J. C.
Heikens, E.
de Brauwer, E. I.G.B.
Stals, F. S.
Silvis, W.
Dorigo-Zetsma, J. W.
Waar, K.
van Mens, S. P.
Roescher, N.
Voss, A.
Wertheim, H.
Slingerland, B. C.G.C.
Frenay, H. M.E.
Schulin, T.
Diederen, B. M.W.
Bode, L.
van Rijn, M.
Dinant, S.
Damen, M.
de Man, P.
Leversteijn-van Hall, M. A.
Dokumenttyp: Artikel
Erscheinungsdatum: 2020
Reihe/Periodikum: Hendrickx , A P A , Landman , F , de Haan , A , Borst , D , Witteveen , S , van Santen-Verheuvel , M G , van der Heide , H G J , Schouls , L M , Halaby , T , Steingrover , R , Cohen Stuart , J W T , Melles , D C , van Dijk , K , Spijkerman , I J B , Notermans , D W , Oudbier , J H , van Ogtrop , M L , van Dam , A , den Reijer , M , Kluytmans , J A J W , van der Linden , M P M , Mattsson , E E , van der Vusse , M , de Jong , E , Maijer-Reuwer , A , van Trijp , M , van Griethuysen , A J , Ott , A , Bathoorn , E , Sinnige , J C , Heikens , E , de Brauwer , E I G B , Stals , F S , Silvis , W , Dorigo-Zetsma , J W , Waar , K , van Mens , S P , Roescher , N , Voss , A , Wertheim , H , Slingerland , B C G C , Frenay , H M E , Schulin , T , Diederen , B M W , Bode , L , van Rijn , M , Dinant , S , Damen , M , de Man , P , Leversteijn-van Hall , M A & Dutch CPE Surveillance Study Group 2020 , ' Plasmid diversity among genetically related Klebsiella pneumoniae bla KPC-2 and bla KPC-3 isolates collected in the Dutch national surveillance ' , Scientific Reports , vol. 10 , no. 1 , 16778 . https://doi.org/10.1038/s41598-020-73440-2
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-29021450
Datenquelle: BASE; Originalkatalog
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Link(s) : https://cris.maastrichtuniversity.nl/en/publications/c72b8e71-a9b4-480a-b1ef-fa11f973f8a9