Opportunities for surgical treatment in metastatic melanoma patients have re-emerged due to the development of novel systemic therapeutics over the past decade. The aim of this study is to present data on outcomes of surgery in patients with unresectable stage IIIC and IV melanoma, who have previously been treated with immunotherapy or targeted therapy. Data was extracted from the Dutch Melanoma Treatment Registry (DMTR) on 154 patients obtaining disease control to systemic therapy and undergoing subsequent surgery. Disease control was defined as a complete response (CR), which was seen in 3.2... Mehr ...
| Verfasser: |
Blankenstein, S.A.
Aarts, M.J.B.
van den Berkmortel, F.W.P.J.
Boers-Sonderen, M.J.
van den Eertwegh, A.J.M.
Franken, M.G.
de Groot, J.W.B.
Haanen, J.B.A.G.
Hospers, G.A.P.
Kapiteijn, E.
Piersma, D.
van Rijn, R.S.
Suijkerbuijk, K.P.M.
ten Tije, A.J.
van der Veldt, A.A.M.
Vreugdenhil, G.
Wouters, M.W.J.M.
van Akkooi, A.C.J. |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2020 |
| Reihe/Periodikum: |
Blankenstein , S A , Aarts , M J B , van den Berkmortel , F W P J , Boers-Sonderen , M J , van den Eertwegh , A J M , Franken , M G , de Groot , J W B , Haanen , J B A G , Hospers , G A P , Kapiteijn , E , Piersma , D , van Rijn , R S , Suijkerbuijk , K P M , ten Tije , A J , van der Veldt , A A M , Vreugdenhil , G , Wouters , M W J M & van Akkooi , A C J 2020 , ' Surgery for Unresectable Stage IIIC and IV Melanoma in the Era of New Systemic Therapy ' , Cancers , vol. 12 , no. 5 , 1176 . https://doi.org/10.3390/cancers12051176 |
| Schlagwörter: |
braf
/ combined nivolumab
/ dabrafenib
/ double-blind
/ dutch melanoma treatment registry
/ ipilimumab
/ metastatic melanoma
/ multicenter
/ open-label
/ phase-3
/ surgery
/ survival
/ systemic therapy |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-29021398 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://cris.maastrichtuniversity.nl/en/publications/ba9cce4c-4c54-4d1b-bc08-80313b5bc19d |
