Tofacitinib for ulcerative colitis: results of the prospective Dutch Initiative on Crohn and Colitis (ICC) registry

Background Tofacitinib is a Janus kinase inhibitor approved for the treatment of ulcerative colitis (UC).Aim To evaluate effectiveness, safety and use of tofacitinib in daily practice.Methods UC patients initiating tofacitinib were prospectively enrolled in 15 hospitals in the Netherlands. Corticosteroid-free clinical remission (short clinical colitis activity index [SCCAI] <= 2), biochemical remission (faecal calprotectin level <= 250 mu g/g), combined corticosteroid-free clinical and biochemical remission, predictors of remission, safety outcomes, treatment dose and effect on lipids we... Mehr ...

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Verfasser: Biemans, V.B.C.
Sleutjes, J.A.M.
de Vries, A.C.
Bodelier, A.G.L.
Dijkstra, G.
Oldenburg, B.
Lowenberg, M.
van Bodegraven, A.A.
van der Meulen-de Jong, A.E.
de Boer, N.K.H.
Srivastava, N.
West, R.L.
Romkens, T.E.H.
Horje, C.H.T.S.
Jansen, J.M.
van der Woude, C.J.
Hoekstra, J.
Weersma, R.K.
van Schaik, F.D.M.
Hoentjen, F.
Pierik, M.J.
Dokumenttyp: Artikel
Erscheinungsdatum: 2020
Reihe/Periodikum: Biemans , V B C , Sleutjes , J A M , de Vries , A C , Bodelier , A G L , Dijkstra , G , Oldenburg , B , Lowenberg , M , van Bodegraven , A A , van der Meulen-de Jong , A E , de Boer , N K H , Srivastava , N , West , R L , Romkens , T E H , Horje , C H T S , Jansen , J M , van der Woude , C J , Hoekstra , J , Weersma , R K , van Schaik , F D M , Hoentjen , F , Pierik , M J & Dutch Initiative Crohn and Colitis 2020 , ' Tofacitinib for ulcerative colitis: results of the prospective Dutch Initiative on Crohn and Colitis (ICC) registry ' , Alimentary Pharmacology & Therapeutics , vol. 51 , no. 9 , pp. 880-888 . https://doi.org/10.1111/apt.15689
Schlagwörter: real world / rheumatoid-arthritis / tofacitinib / ulcerative colitis
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-29021275
Datenquelle: BASE; Originalkatalog
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Link(s) : https://cris.maastrichtuniversity.nl/en/publications/985b42e1-6c0c-4e70-b07c-adfaf197fe59