eQTL mapping and colocalization of fine-mapping and eQTL mapping results for GC and the non-coding RNA.

(A) A Schematic overview of the GC gene structure and position of the GC CNV. Our data detected two GC transcripts, where the canonical form account the majority of the expression (98%) and an alternative form only counting for minor expression (2%). (B) eQTL was mapped for the genes located in a 2-Mb bin (BTA6:87.68–89.68). Of the 13 genes annotated in this bin, GC showed predominantly high expression (5,000 TPM <), whereas the rest were lowly expressed or not expressed at all. The eQTL were mapped for GC and SLC4A4 . (C) CM resistance fine-mapping results were shown for the 2-Mb bin, wher... Mehr ...

Verfasser: Young-Lim Lee (8371320)
Haruko Takeda (814623)
Gabriel Costa Monteiro Moreira (5821850)
Latifa Karim (139538)
Erik Mullaart (139555)
Wouter Coppieters (38045)
Ruth Appeltant (11167410)
Roel F. Veerkamp (8395314)
Martien A. M. Groenen (7876013)
Michel Georges (69807)
Mirte Bosse (116283)
Tom Druet (147465)
Aniek C. Bouwman (8778752)
Carole Charlier (139517)
Dokumenttyp: Image
Erscheinungsdatum: 2021
Schlagwörter: Genetics / Neuroscience / Evolutionary Biology / Cancer / Infectious Diseases / Plant Biology / Virology / Environmental Sciences not elsewhere classified / Biological Sciences not elsewhere classified / dairy cattle Clinical mastitis / multiplicated allele / SNP / vitamin D pathway / vitamin D binding protein / group-specific component gene / Dutch dairy cattle population / CM resistance QTL / GC gene enhancer / CNV / dairy cattle breeds / variant / 12 kb multi-allelic copy number var. / expression QTL mapping
Sprache: unknown
Permalink: https://search.fid-benelux.de/Record/base-29019096
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://doi.org/10.1371/journal.pgen.1009331.g005