eQTL mapping and colocalization of fine-mapping and eQTL mapping results for GC and the non-coding RNA.
(A) A Schematic overview of the GC gene structure and position of the GC CNV. Our data detected two GC transcripts, where the canonical form account the majority of the expression (98%) and an alternative form only counting for minor expression (2%). (B) eQTL was mapped for the genes located in a 2-Mb bin (BTA6:87.68–89.68). Of the 13 genes annotated in this bin, GC showed predominantly high expression (5,000 TPM <), whereas the rest were lowly expressed or not expressed at all. The eQTL were mapped for GC and SLC4A4 . (C) CM resistance fine-mapping results were shown for the 2-Mb bin, wher... Mehr ...
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Dokumenttyp: | Image |
Erscheinungsdatum: | 2021 |
Schlagwörter: | Genetics / Neuroscience / Evolutionary Biology / Cancer / Infectious Diseases / Plant Biology / Virology / Environmental Sciences not elsewhere classified / Biological Sciences not elsewhere classified / dairy cattle Clinical mastitis / multiplicated allele / SNP / vitamin D pathway / vitamin D binding protein / group-specific component gene / Dutch dairy cattle population / CM resistance QTL / GC gene enhancer / CNV / dairy cattle breeds / variant / 12 kb multi-allelic copy number var. / expression QTL mapping |
Sprache: | unknown |
Permalink: | https://search.fid-benelux.de/Record/base-29019096 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://doi.org/10.1371/journal.pgen.1009331.g005 |