In the Netherlands land subsidence is a continuously ongoing process. Consequently, an increasing number of people and economic assets are exposed to subsidence, damage costs are soaring, and flood risk and greenhouse gas emissions are increasing. In some areas tipping points have already been reached, where current land-use can no longer be maintained without considerable costs, underlining the urgency to take action. Together with a consortium consisting of universities, research institutes, governmental agencies, public and private partners we have developed a national, multidisciplinary research programme aiming to develop an integrative approach to achieve feasible, legitimate and sustainable solutions for managing the negative societal effects of land subsidence, connecting fundamental research on subsidence processes to socio-economic impact of subsidence and to governance and legal framework design. The program is designed to co-create insights that help to effectively mitigate and adapt to subsidence within the Netherlands by making major improvements in measuring and modeling the processes and consequences of subsidence, identifying, developing and critically evaluating control measures and designing governance and legal approaches that facilitate their implementation. Hereto we will develop (a) new satellite-based technology to measure, attribute and monitor subsidence, (b) solid understanding of the interacting multiple processes contributing to total subsidence, (c) sophisticated physical and economic numerical models to predict human-induced subsidence rates and impacts, and (d) implementation strategies that go beyond technical measures, to strengthen governance and financing capacities as well as legal frameworks. This fully integrated approach deals with all impacts of land subsidence on society and the economy.