Validation and reliability of the Dutch version of the EORTC QLQ-NMIBC24 Questionnaire Module for patients with non-muscle-invasive bladder cancer

Background: The European Organisation for Research and Treatment of Cancer (EORTC) quality of life questionnaire for non-muscle invasive bladder cancer (QLQ-NMIBC24) has been available and applied for some years now, but has yet to undergo a full comprehensive psychometric evaluation. The aim of this study was to investigate the psychometric properties of the Dutch version of the EORTC QLQ-NMIBC24 questionnaire in patients with low, intermediate and high risk NMIBC. Methods: We included patients newly diagnosed with NMIBC participating in the multicenter, population-based prospective cohort st... Mehr ...

Verfasser: Ripping, Theodora M.
Westhoff, Ellen
Aaronson, Neil K.
Van Hemelrijck, Mieke
Rammant, Elke
Witjes, J. Alfred
Kiemeney, Lambertus A.
Aben, Katja K.H.
Vrieling, Alina
Dokumenttyp: Artikel
Erscheinungsdatum: 2021
Reihe/Periodikum: Ripping , T M , Westhoff , E , Aaronson , N K , Van Hemelrijck , M , Rammant , E , Witjes , J A , Kiemeney , L A , Aben , K K H & Vrieling , A 2021 , ' Validation and reliability of the Dutch version of the EORTC QLQ-NMIBC24 Questionnaire Module for patients with non-muscle-invasive bladder cancer ' , Journal of Patient-Reported Outcomes , vol. 5 , no. 1 , 96 . https://doi.org/10.1186/s41687-021-00372-4
Schlagwörter: Bladder cancer / EORTC questionnaire / Quality of life / Validation studies
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-28995051
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://kclpure.kcl.ac.uk/portal/en/publications/validation-and-reliability-of-the-dutch-version-of-the-eortc-qlqnmibc24-questionnaire-module-for-patients-with-nonmuscleinvasive-bladder-cancer(d9781ffb-4e67-441d-b7d7-87631eaff7f5).html

Background: The European Organisation for Research and Treatment of Cancer (EORTC) quality of life questionnaire for non-muscle invasive bladder cancer (QLQ-NMIBC24) has been available and applied for some years now, but has yet to undergo a full comprehensive psychometric evaluation. The aim of this study was to investigate the psychometric properties of the Dutch version of the EORTC QLQ-NMIBC24 questionnaire in patients with low, intermediate and high risk NMIBC. Methods: We included patients newly diagnosed with NMIBC participating in the multicenter, population-based prospective cohort studies UroLife or BlaZIB. Psychometric evaluation included examination of the structural validity, reliability (i.e. internal consistency and test–retest reliability), construct validity (i.e. divergent validity and known-groups validity), responsiveness and interpretability. Results: A total of 1463 patients who completed the baseline questionnaire of UroLife (n = 541, response rate 50%) or BlaZIB (n = 922, response rate 58%) were included. The percentage of missing responses were low for all non-sex related scales (< 1%) and ranged between 6.9% to 50.0% for sex-related scales. More than 15% of the patients obtained the lowest possible scores on nearly each scale (floor effect). The structural validity was adequate; the confirmatory factor analysis showed satisfactory results and all items of multiple items scales had higher within- than between-scale correlations. Reliability of the questionnaire was adequate for most multiple item scales (Cronbach’s α ≥ 0.70 and intraclass correlation coefficient ≥ 0.70), with exception of the scales ‘malaise’ and ‘bloating and flatulence’. The questionnaire also showed good construct validity; it showed low correlations with the items of the EORTC core questionnaire and was able to measure differences between risk-based subgroups. The responsiveness of the questionnaire was good, but the interpretability, i.e. minimal important change, could not be determined. Conclusions: This study ...