External validation of prognostic models for preeclampsia in a Dutch multicenter prospective cohort ...

Objective : To perform an external validation of all published prognostic models for first-trimester prediction of the risk of developing preeclampsia (PE). Methods : Women <14 weeks of pregnancy were recruited in the Netherlands. All systematically identified prognostic models for PE that contained predictors commonly available were eligible for external validation. Results : 3,736 women were included; 87 (2.3%) developed PE. Calibration was poor due to overestimation. Discrimination of 9 models for LO-PE ranged from 0.58 to 0.71 and of 9 models for all PE from 0.55 to 0.75. Conclusion : O... Mehr ...

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Verfasser: Ruiter, Marije Lamain-De
Kwee, Anneke
Naaktgeboren, Christiana A.
Louhanepessy, Rebecca D.
Groot, Inge De
Evers, Inge M.
Groenendaal, Floris
Hering, Yolanda R.
Anjoke J. M. Huisjes
Kirpestein, Cornel
Monincx, Wilma M.
Schielen, Peter C. J. I.
Annewil Van ’T Zelfde
Oirschot, Charlotte M. Van
Vankan-Buitelaar, Simone A.
Vonk, Mariska A. A. W.
Wiegers, Therese A.
Zwart, Joost J.
Moons, Karel G. M.
Franx, Arie
Koster, Maria P. H.
Dokumenttyp: dataset
Erscheinungsdatum: 2019
Verlag/Hrsg.: Taylor & Francis
Schlagwörter: Cell Biology / Genetics / FOS: Biological sciences / Biotechnology / Immunology / FOS: Clinical medicine / 69999 Biological Sciences not elsewhere classified / 80699 Information Systems not elsewhere classified / FOS: Computer and information sciences / 19999 Mathematical Sciences not elsewhere classified / FOS: Mathematics / Cancer / Science Policy / Hematology
Sprache: unknown
Permalink: https://search.fid-benelux.de/Record/base-28983414
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://dx.doi.org/10.6084/m9.figshare.7871354.v1

Objective : To perform an external validation of all published prognostic models for first-trimester prediction of the risk of developing preeclampsia (PE). Methods : Women <14 weeks of pregnancy were recruited in the Netherlands. All systematically identified prognostic models for PE that contained predictors commonly available were eligible for external validation. Results : 3,736 women were included; 87 (2.3%) developed PE. Calibration was poor due to overestimation. Discrimination of 9 models for LO-PE ranged from 0.58 to 0.71 and of 9 models for all PE from 0.55 to 0.75. Conclusion : Only a few easily applicable prognostic models for all PE showed discrimination above 0.70, which is considered an acceptable performance. ...