Lessons learned from clinical phenotypes in early psoriatic arthritis: the real-world Dutch south west Early Psoriatic ARthritis study ...

Objective: This paper describes the baseline demographics, clinical characteristics, and patient-reported outcomes (PROs) according to clinical phenotype of patients with early psoriatic arthritis (PsA) for the purpose of creating a decision support system for daily clinical practice. Method: Patients with newly diagnosed PsA were included in the Dutch south west Early Psoriatic ARthritis (DEPAR) study. No classification criteria were applied, to ensure collection of real-world data on demographics, medication, clinical characteristics, and PROs. An IT infrastructure facilitated data collectio... Mehr ...

Verfasser: FR Kasiem
JJ Luime
M Vis
MR Kok
K Wervers
AH Gerards
CWY Appels
WL Van Der Graaff
MJF Starmans-Kool
YPM Goekoop-Ruiterman
JHLM Van Groenendael
L-A Korswagen
JJ Veris-Van Dieren
JMW Hazes
I Tchetverikov
Dokumenttyp: Journal contribution
Erscheinungsdatum: 2020
Verlag/Hrsg.: Taylor & Francis
Schlagwörter: Medicine / Biotechnology / Ecology / FOS: Biological sciences / Immunology / FOS: Clinical medicine / Cancer / 111714 Mental Health / FOS: Health sciences / Hematology
Sprache: unknown
Permalink: https://search.fid-benelux.de/Record/base-28982018
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://dx.doi.org/10.6084/m9.figshare.13122123.v1

Objective: This paper describes the baseline demographics, clinical characteristics, and patient-reported outcomes (PROs) according to clinical phenotype of patients with early psoriatic arthritis (PsA) for the purpose of creating a decision support system for daily clinical practice. Method: Patients with newly diagnosed PsA were included in the Dutch south west Early Psoriatic ARthritis (DEPAR) study. No classification criteria were applied, to ensure collection of real-world data on demographics, medication, clinical characteristics, and PROs. An IT infrastructure facilitated data collection. Results: We described 527 patients, categorized according to the clinical phenotype stated by the rheumatologist at the time of diagnosis, namely monoarthritis (15%), oligoarthritis (40%), polyarthritis (23%), enthesitis (10%), axial disease (2%), and dactylitis (10%). Overall psoriasis severity was mild and 83 patients (16%) had no psoriasis. Short-term sick leave (> 1 day per 4 weeks) was 17% and long-term sick ...