Additional file 1 of Neuropathological correlates of parkinsonian disorders in a large Dutch autopsy series ...

Additional file 1 Supplementary Figure 1. When clustering all donors with a complete dataset (n = 164) based on clinical features and pathological stages, four clusters of donors can be distinguished, namely 1) a small cluster with high AD-type pathology, 2) a cluster with LP donors (except for 2 non-LP donors) with an early disease onset, a young age at death and relatively little AD-type pathology, 3) a cluster with almost all non-LP donors, and 4) a cluster with LP donors (except for 1 non-LP donor) with a late age at onset and a late age at death. Supplementary Figure 2. When clustering on... Mehr ...

Verfasser: H. Geut
D. H. Hepp
E. Foncke
H. W. Berendse
J. M. Rozemuller
I. Huitinga
W. D. J. Van De Berg
Dokumenttyp: Journal contribution
Erscheinungsdatum: 2020
Verlag/Hrsg.: figshare
Schlagwörter: Biophysics / Medicine / Cell Biology / Molecular Biology / Neuroscience / Immunology / FOS: Clinical medicine / 111714 Mental Health / FOS: Health sciences / Hematology
Sprache: unknown
Permalink: https://search.fid-benelux.de/Record/base-28981918
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://dx.doi.org/10.6084/m9.figshare.12038325

Additional file 1 Supplementary Figure 1. When clustering all donors with a complete dataset (n = 164) based on clinical features and pathological stages, four clusters of donors can be distinguished, namely 1) a small cluster with high AD-type pathology, 2) a cluster with LP donors (except for 2 non-LP donors) with an early disease onset, a young age at death and relatively little AD-type pathology, 3) a cluster with almost all non-LP donors, and 4) a cluster with LP donors (except for 1 non-LP donor) with a late age at onset and a late age at death. Supplementary Figure 2. When clustering only the LP donors with a complete dataset (n = 98), Braak α-synuclein stages and neocortical LP are most closely related to Braak NFT stage and dementia. ...