Changes in Version 4 Link to reviewer comments and responses on PCI_Archaeology will be added. In the meantime you can view compare the files here: https://github.com/bbartholdy/mb11CalculusPilot/compare/f373fe79a93b5ed57f76fa85499ca8a52726f486..9dc7de090db2c4181c6bdf6e02e7ce19ac7d3114?diff=unified#diff-3b8129ca3cee54d1b59a9c45e353de87085826397c9142046806d5cc7df0971f Changes in Version 3 Added authors (oops) and affiliations to first page Changes in Version 2 Added section for disclosing conflicts of interest required for PCI_Archaeology submission. Caries ratio recalculated - Downstream effects: caries and calculus (presence/absence) no longer correlated Site-wide caries ratio increased from 12.7% to 17.6% No other relevant changes in values as a result. Abstract Dental calculus is an excellent source of information on the dietary patterns of past populations, including consumption of plant-based items. The detection of plant-derived residues such as alkaloids and their metabolites in dental calculus ...