Model-based effectiveness and cost-effectiveness of risk-based selection strategies for adjuvant chemotherapy in Dutch stage II colon cancer patients ...
Background:We aimed to evaluate the cost-effectiveness of risk-based strategies to improve the selection of surgically treated stage II colon cancer (CC) patients for adjuvant chemotherapy.Methods:Using the ‘Personalized Adjuvant TreaTment in EaRly stage coloN cancer’ (PATTERN) model, we evaluated five selection strategies: (1) no chemotherapy, (2) Dutch guideline recommendations assuming observed adherence, (3) Dutch guideline recommendations assuming perfect adherence, (4) biomarker mutation OR pT4 stage strategy in which patients with MSS status combined with a pT4 stage or a mutation in BR... Mehr ...
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| Dokumenttyp: | Datenquelle |
| Erscheinungsdatum: | 2021 |
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SAGE Journals
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| Schlagwörter: | 111199 Nutrition and Dietetics not elsewhere classified / FOS: Health sciences / 111299 Oncology and Carcinogenesis not elsewhere classified / FOS: Clinical medicine / 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified |
| Sprache: | unknown |
| Permalink: | https://search.fid-benelux.de/Record/base-28979992 |
| Datenquelle: | BASE; Originalkatalog |
| Powered By: | BASE |
| Link(s) : | https://dx.doi.org/10.25384/sage.c.5337760 |
