Can linguistic variables make a difference: differentiating primary progressive aphasias in Dutch speakers using semi-spontaneous language production ...

Primary progressive aphasia (PPA) is a clinical syndrome, characterized by a gradual but progressive deterioration of speech and language function. There are three main accepted variants: (1) non-fluent/agrammatic, (2) semantic and (3) logopenic variant. Until now, differentiation of these variants remains challenging, especially for non-fluent vs logopenic. However, it is of great importance for prognosis and treatment. Recent evidence suggests the usefulness of linguistic analysis of semi-spontaneous language production in the diagnostic process of the disease. However, the vast majority of... Mehr ...