Emergence of NDM-1-Producing Enterobacteriaceae in Belgium

ABSTRACT Five multidrug-resistant nonclonally related Enterobacteriaceae isolates were recovered in Belgium in 2010 from three patients who had been hospitalized in Pakistan, Montenegro, and Serbia/Kosovo. New Delhi metallo-β-lactamase (NDM-1) was detected in each of the isolates in addition to several extended-spectrum β-lactamases (CTX-M-15, SHV-12), plasmidic cephalosporinases (CMY-16, CMY-58), rRNA methylases (ArmA, RmtB), and Qnr genes ( qnrA6 , qnrB1 , qnrB2 ). One patient died from uncontrolled sepsis, while the two others recovered. No secondary cases occurred in any of the hospitals.... Mehr ...

Verfasser: Bogaerts, Pierre
Bouchahrouf, Warda
de Castro, Roberta Rezende
Deplano, Ariane
Berhin, Catherine
Piérard, Denis
Denis, Olivier
Glupczynski, Youri
Dokumenttyp: Artikel
Erscheinungsdatum: 2011
Reihe/Periodikum: Antimicrobial Agents and Chemotherapy ; volume 55, issue 6, page 3036-3038 ; ISSN 0066-4804 1098-6596
Verlag/Hrsg.: American Society for Microbiology
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-28946080
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : http://dx.doi.org/10.1128/aac.00049-11

ABSTRACT Five multidrug-resistant nonclonally related Enterobacteriaceae isolates were recovered in Belgium in 2010 from three patients who had been hospitalized in Pakistan, Montenegro, and Serbia/Kosovo. New Delhi metallo-β-lactamase (NDM-1) was detected in each of the isolates in addition to several extended-spectrum β-lactamases (CTX-M-15, SHV-12), plasmidic cephalosporinases (CMY-16, CMY-58), rRNA methylases (ArmA, RmtB), and Qnr genes ( qnrA6 , qnrB1 , qnrB2 ). One patient died from uncontrolled sepsis, while the two others recovered. No secondary cases occurred in any of the hospitals.