Le sevrage ultra-rapide des toxicomanes aux opiaciés sous anesthiésie géniérale: Résultats préliminaires du protocole Liègeois ; Ultra-Rapid Opiate Detoxification under general Anaesthesia: Preliminary results of the Liège trial

peer reviewed ; Many studies support the hypothesis of a substantial benefit in inducing an Opiate Receptor Blockade through a Rapid Opiate Detoxification under general Anaesthesia (RODA) in opiate dependent patients. However, prospective studies and long term evaluation of the technique are lacking. In order to evaluate long-term abstinence rates after a RODA among a sample of opiate addicts, a study was started in March 1999 at the University of Liège. To date, 45 patients were evaluated (mean age: 29 ± 5 years) with a mean opiate dependence duration of 8 ± 4 years. Most of them were both he... Mehr ...

Verfasser: Pinto, Emmanuel
Reggers, Jean
Delhez, Michèle
Fuchs, Sonia
VENNEMAN, Ingrid
Lamy, Maurice
ANSSEAU, Marc
Dokumenttyp: journal article
Erscheinungsdatum: 2001
Verlag/Hrsg.: Université de Liège. Revue Médicale de Liège
Schlagwörter: Anaesthesia / Naltrexone / Opiate dependence / Opiate withdrawal / RODA / Adult / Anesthesia / General / Belgium / Clinical Protocols / Female / Humans / Male / Opioid-Related Disorders / Time Factors / Human health sciences / Pharmacy / pharmacology & toxicology / Sciences de la santé humaine / Pharmacie / pharmacologie & toxicologie
Sprache: Französisch
Permalink: https://search.fid-benelux.de/Record/base-28941192
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://orbi.uliege.be/handle/2268/262152

peer reviewed ; Many studies support the hypothesis of a substantial benefit in inducing an Opiate Receptor Blockade through a Rapid Opiate Detoxification under general Anaesthesia (RODA) in opiate dependent patients. However, prospective studies and long term evaluation of the technique are lacking. In order to evaluate long-term abstinence rates after a RODA among a sample of opiate addicts, a study was started in March 1999 at the University of Liège. To date, 45 patients were evaluated (mean age: 29 ± 5 years) with a mean opiate dependence duration of 8 ± 4 years. Most of them were both heroin and methadone dependent; 42.2% of them were included while 31.1% did not complete the whole inclusion procedure and 26.7 % were excluded. None experienced severe withdrawal symptoms. At six months, abstinence rate was 67 % and 46 % at one year. These preliminary results suggest the interest of the procedure in carefully selected patients.