The purpose of this research is to determine the most impactful and important source of environmental change at the neighborhood level. The study of multiple scenarios allows us to determine the influence of several parameters on the results of the life cycle analysis of the neighborhood. We are looking at quantifying the impact of orientation, storm water management, density, mobility and the use of renewable energies on the environmental balance sheet of a neighborhood, based on eleven environmental indicators. An eco-neighborhood, located in Belgium, has been selected as the modeling site. The results show that the management of mobility is the parameter that can reduce the impact the most, in terms of greenhouse effect, odor, damage to biodiversity and health. With the adaptation of photovoltaic panels on the site, the production exceeds the consumption all through the year, except for the months of December and January, when the installation covers 45% and 75% of the consumption, respectively. Increasing the built density of the neighborhood by roof stacking allows the different environmental impacts, calculated per inhabitant, to be homogeneously minimized.