Why do men and women vote for the populist radical right? This question, which speaks to the phenomenon of the “radical right gender gap”, has been the topic of much scholarly interest. While previous studies refer to the role played by differences in political resources, attitudes, and socialization, this paper examines whether negative emotions towards the political system, and system-directed anger in particular, drive support for populist radical right parties differently for men and women. Drawing on the premise that populist radical right parties tend to appeal to angry voters, and given that acting upon anger is seen as an “agentic” trait, we expect that system-directed anger is more strongly associated with support for populist radical right parties among men compared to women. We test the hypothesis using original data from the RepResent voter survey organized in Belgium during the 2019 federal elections. In line with previous studies, we find that voters of the populist radical right party Vlaams Belang report high levels of system-directed anger. Men and women voters are similar in their display of this emotion, and contrary to our expectations, they are similar in how system-directed anger relates to vote choice as well. More than explaining gender differences in populist radical right voting, our findings confirm the idea that system-directed anger can incite women as well as men to cast a populist radical right vote.