Growth response of syndromic versus non-syndromic children born small for gestational age (SGA) to growth hormone therapy: a Belgian study

IntroductionA substantial proportion of SGA patients present with a syndrome underlying their growth restriction. Most SGA cohorts comprise both syndromic and non-syndromic patients impeding delineation of the recombinant human growth hormone (rhGH) response. We present a detailed characterization of a SGA cohort and analyze rhGH response based on adult height (AH).MethodsClinical and auxological data of SGA patients treated with rhGH, who had reached AH, were retrieved from BELGROW, a national database of all rhGH treated patients held by BESPEED (BElgian Society for PEdiatric Endocrinology a... Mehr ...

Verfasser: Marianne Becker
Muriel Thomas
Cécile Brachet
Claudine Heinrichs
Hilde Dotremont
Jean De Schepper
Philippe Lysy
Dominique Beckers
the BESPEED group
Anne Rochtus
Anne-Simone Parent
Daniel Klink
Guy Massa
Karl Logghe
Kathleen De Waele
Kristina Casteels
Martine Cools
Willem Staels
Dokumenttyp: Artikel
Erscheinungsdatum: 2023
Reihe/Periodikum: Frontiers in Endocrinology, Vol 14 (2023)
Verlag/Hrsg.: Frontiers Media S.A.
Schlagwörter: short for gestational age / syndromic / growth hormone / growth / children / adult height / Diseases of the endocrine glands. Clinical endocrinology / RC648-665
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-28886538
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://doi.org/10.3389/fendo.2023.1112938