Transmission of primary resistance mutation K103N in a cluster of Belgian young patients from different risk groups
Background: We analysed the distribution of an HIV-1 subtype B strain resistant to efavirenz and nevirapine among incident infections in the Belgian population. Method: The Belgian AIDS reference laboratories searched their databases for HIV-1 subtype B sequences harbouring the K103N mutation in the reverse transcriptase (RT) or the C67S and V77I mutations in the protease (PR). We included the earliest RT sequence available of drug-naïve patients as well as sequences related to treatment failure. Fifty sequences were aligned omitting the codon 103 and submitted to phylogenetic analysis. Epidem... Mehr ...
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Dokumenttyp: | conference |
Erscheinungsdatum: | 2012 |
Schlagwörter: | Medicine and Health Sciences |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-28878458 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://biblio.ugent.be/publication/3141450 |