Migraine is the most common brain disorder, affecting approximately 14% of the adult population, but its molecular mechanisms are poorly understood. We report the results of a meta-analysis across 29 genome-wide association studies, including a total of 23,285 individuals with migraine (cases) and 95,425 population-matched controls. We identified 12 loci associated with migraine susceptibility (P < 5 × 10
Verfasser: |
Anttila, V.
Winsvold, B.S.
Gormley, P.
Kurth, T.
Bettella, F.
McMahon, G.
Kallela, M.
Malik, R.
de Vries, B.
Terwindt, G.
Medland, S.E.
Todt, U.
McArdle, W.L.
Quaye, L.
Koiranen, M.
Ikram, M.A.
Lehtimäki, T.
Stam, A.H.
Ligthart, L.
Wedenoja, J.
Dunham, I.
Neale, B. M.
Palta, P.
Hamalainen, E.
Schürks, M.
Rose, L.M.
Buring, J.E.
Ridker, P.M.
Steinberg, S.
Stefansson, H.
Jakobsson, F.
Lawlor, D.A.
Evans, D.M.
Ring, S.M.
Färkkilä, M.
Artto, V.
Kaunisto, M.A.
Freilinger, T.
Schoenen, J.
Frants, R.R.
Pelzer, N.
Weller, C.M.
Zielman, R.
Heath, A.C.
Madden, P.A.F.
Montgomery, G.W.
Martin, N.G.
Borck, G.
Göbel, H.
Heinze, A.
Heinze-Kuhn, K.
Williams, F.M.
Hartikainen, A.-L.
Pouta, A.
van den Ende, J.
Uitterlinden, A.G.
Hofman, A.
Amin, N.
Hottenga, J.J.
Vink, J.M.
Heikkilä, K.
Alexander, M.
Muller-Myhsok, B.
Schreiber, S
Meitinger, T.
Wichmann, H. E.
Aromaa, A.
Eriksson, J.G.
Traynor, B.J.
Trabzuni, D.
Rossin, E.
Lage, K.
Jacobs, S.B.
Gibbs, J.R.
Birney, E.
Kaprio, J.
Penninx, B.W.J.H.
Boomsma, D.I.
van Duijn, C.M.
Raitakari, O.
Jarvelin, M.-R.
Zwart, J.A.
Cherkas, L.
Strachan, D.P.
Kubisch, C.
Ferrari, M.D.
van den Maagdenberg, A.M.J.M.
Dichgans, M.
Wessman, M.
Smith, G.D.
Stefansson, K.
Daly, M.J.
Nyholt, DR
Chasman, D.I.
Palotie, A. |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2013 |
Reihe/Periodikum: |
Anttila , V , Winsvold , B S , Gormley , P , Kurth , T , Bettella , F , McMahon , G , Kallela , M , Malik , R , de Vries , B , Terwindt , G , Medland , S E , Todt , U , McArdle , W L , Quaye , L , Koiranen , M , Ikram , M A , Lehtimäki , T , Stam , A H , Ligthart , L , Wedenoja , J , Dunham , I , Neale , B M , Palta , P , Hamalainen , E , Schürks , M , Rose , L M , Buring , J E , Ridker , P M , Steinberg , S , Stefansson , H , Jakobsson , F , Lawlor , D A , Evans , D M , Ring , S M , Färkkilä , M , Artto , V , Kaunisto , M A , Freilinger , T , Schoenen , J , Frants , R R , Pelzer , N , Weller , C M , Zielman , R , Heath , A C , Madden , P A F , Montgomery , G W , Martin , N G , Borck , G , Göbel , H , Heinze , A , Heinze-Kuhn , K , Williams , F M , Hartikainen , A-L , Pouta , A , van den Ende , J , Uitterlinden , A G , Hofman , A , Amin , N , Hottenga , J J , Vink , J M , Heikkilä , K , Alexander , M , Muller-Myhsok , B , Schreiber , S , Meitinger , T , Wichmann , H E , Aromaa , A , Eriksson , J G , Traynor , B J , Trabzuni , D , Rossin , E , Lage , K , Jacobs , S B , Gibbs , J R , Birney , E , Kaprio , J , Penninx , B W J H , Boomsma , D I , van Duijn , C M , Raitakari , O , Jarvelin , M-R , Zwart , J A , Cherkas , L , Strachan , D P , Kubisch , C , Ferrari , M D , van den Maagdenberg , A M J M , Dichgans , M , Wessman , M , Smith , G D , Stefansson , K , Daly , M J , Nyholt , DR , Chasman , D I & Palotie , A 2013 , ' Genome-wide meta-analysis identifies new susceptibility loci for migraine ' , Nature Genetics , vol. 45 , no. 8 , pp. 912-917 . https://doi.org/10.1038/ng.2676 |
Schlagwörter: |
/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_
/ name=Netherlands Twin Register (NTR)
/ /dk/atira/pure/sustainabledevelopmentgoals/reduced_inequalities
/ name=SDG 10 - Reduced Inequalities |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-28797859 |
Datenquelle: |
BASE;
Originalkatalog |
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BASE |
Link(s) :
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https://research.vu.nl/en/publications/1a3decb8-3e1d-45d5-9c2f-f958d4d80c9c |