Development and persistence of resistance to fungicides in Sphaerotheca fuliginea in cucumbers in the Netherlands

Ergosterol biosynthesis inhibitors (EBIs) have a remarkably broad spectrum of antifungal activity. They belong to the commercial fungicides which exhibit the highest activity known to date. Resistance to EBIs was found in vitro, but the level of resistance and the decreased fitness of resistant strains led to the hypothesis that resistance to EBIs was rather unlikely to develop in practice. Despite the fact that EBIs were introduced as early as 1972, up to 1980 only data on EBI-resistant laboratory strains were available. However, gradually there appeared reports on decreased sensitivity to EB... Mehr ...