Transcriptomic analysis of non-invasive infections by Aspergillus fumigatus: The case of sino-nasal aspergillosis (SNA) in dogs
Objective: The form of human fungal sinusitis that most closely approximates the disease occurring in the dog is chronic erosive non-invasive fungal sinusitis. This disease is characterized by final destruction of bone in the absence of tissue invasion by the fungus and requires both removal of fungal plaques, necrotic tissue and medical therapy with antifungals. Remarkably, these fungal plaques are white indicated that asexual development does not proceed in the patients. Immune response in SNA infections has been studied via biopsy and cytokine profiling as well as transcriptomic analysis of... Mehr ...
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Dokumenttyp: | Abstract |
Erscheinungsdatum: | 2018 |
Schlagwörter: | antifungal agent / catalase / cytokine / endogenous compound / liquid nitrogen / superoxide dismutase / transcriptome / adult / animal experiment / animal model / animal tissue / asexual reproduction / aspergillosis / biofilm / biopsy / cleaning / conference abstract / controlled study / dog / drug therapy / endoscope / female / genetic transcription / immune response / male / Netherlands / nonhuman / RNA isolation / secondary metabolism / signal transduction / sporogenesis / stable expression / stress / surgery / virulence / Taverne |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-28789290 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://dspace.library.uu.nl/handle/1874/369045 |