Androgen deprivation therapy for androgen receptor-positive advanced salivary duct carcinoma:A nationwide case series of 35 patients in The Netherlands

BackgroundSalivary duct carcinoma, an aggressive subtype of salivary gland cancer, is mostly androgen receptor-positive. Only limited data are available on androgen deprivation therapy (ADT). MethodsPatients with advanced androgen receptor-positive salivary duct carcinoma treated with first-line ADT were retrospectively evaluated for clinical benefit (ie, partial response [PR] and stable disease, progression-free survival [PFS] and overall survival [OS]). The OS was compared with patients with advanced salivary duct carcinoma who received best supportive care. ResultsThirty-four of 35 patients... Mehr ...

Verfasser: Boon, Eline
van Boxtel, Wim
Buter, Jan
de Jong, Robert J. Baatenburg
van Es, Robert J. J.
Bel, Miranda
Fiets, Edward
Oosting, Sjoukje F.
Slingerland, Marije
Hoeben, Ann
Tesselaar, Margot E. T.
Jonker, Marianne A.
Flucke, Uta E.
van der Graaf, Winette T. A.
van Herpen, Carla M. L.
Dokumenttyp: Artikel
Erscheinungsdatum: 2018
Reihe/Periodikum: Boon , E , van Boxtel , W , Buter , J , de Jong , R J B , van Es , R J J , Bel , M , Fiets , E , Oosting , S F , Slingerland , M , Hoeben , A , Tesselaar , M E T , Jonker , M A , Flucke , U E , van der Graaf , W T A , van Herpen , C M L & Nationwide Network; Registry Histopathology Cytopathol 2018 , ' Androgen deprivation therapy for androgen receptor-positive advanced salivary duct carcinoma : A nationwide case series of 35 patients in The Netherlands ' , Head and Neck-Journal for the Sciences and Specialties of the Head and Neck , vol. 40 , no. 3 , pp. 605-613 . https://doi.org/10.1002/hed.25035
Schlagwörter: androgen deprivation therapy / androgen receptors / antineoplastic agents / hormonal / salivary duct carcinoma / salivary gland neoplasms / TRASTUZUMAB / COMBINATION / CANCERS / HER2
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-28775036
Datenquelle: BASE; Originalkatalog
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Link(s) : https://cris.maastrichtuniversity.nl/en/publications/96b4153d-89cf-49b4-90a7-82e16c18d438