Conditional relative survival among patients with chronic lymphocytic leukaemia: A population‐based study in the Netherlands

Abstract Studies on conditional relative survival (CRS) in chronic lymphocytic leukaemia (CLL) have hitherto been lacking in the literature. We predicted up‐to‐date estimates of 5‐year RS at diagnosis and for each additional year survived (i.e., CRS) up to 15 years post‐diagnosis among CLL patients diagnosed during 2007–2020. We showed that 5‐year CRS continues to decline gradually with each additional year survived in a contemporary era with access to novel‐based agents, irrespective of age. This finding indicates that CLL patients continue to experience substantial excess mortality compared... Mehr ...

Verfasser: Lina van derStraten
Mark‐David Levin
Otto Visser
Eduardus F.M. Posthuma
Jeanette K. Doorduijn
Arnon P. Kater
Avinash G. Dinmohamed
Dokumenttyp: Artikel
Erscheinungsdatum: 2022
Reihe/Periodikum: eJHaem, Vol 3, Iss 1, Pp 180-183 (2022)
Verlag/Hrsg.: Wiley
Schlagwörter: cancer epidemiology / chronic lymphocytic leukaemia / conditional survival / population‐based registry / relative survival / Diseases of the blood and blood-forming organs / RC633-647.5
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-28760975
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://doi.org/10.1002/jha2.368

Abstract Studies on conditional relative survival (CRS) in chronic lymphocytic leukaemia (CLL) have hitherto been lacking in the literature. We predicted up‐to‐date estimates of 5‐year RS at diagnosis and for each additional year survived (i.e., CRS) up to 15 years post‐diagnosis among CLL patients diagnosed during 2007–2020. We showed that 5‐year CRS continues to decline gradually with each additional year survived in a contemporary era with access to novel‐based agents, irrespective of age. This finding indicates that CLL patients continue to experience substantial excess mortality compared to an age‐ and sex‐matched group from the general population.