Case report: Coxiella burnetii vascular infection and lymphoma in the Netherlands

International audience ; Non-Hodgkin lymphoma has been linked to infection with Coxiella burnetii, potentially through overproduction of IL-10 during infection with C. burnetii. Description of a case report. We describe a patient with retroperitoneal non-Hodgkin lymphoma and vascular infection with C. burnetii. Immunofluorescence staining and fluorescence in situ hybridization targeting specific C. burnetii 16S rRNA were performed on the retroperitoneal lymphoma tissue sample obtained at diagnosis of NHL. Both were strongly positive for the presence of C. burnetii. This case provokes questions... Mehr ...

Verfasser: Roeden, Sonja E.,
Melenotte, Clea
Hermans, Mirjam H. A.
Sinnige, Harm A. M.
Nooijen, Peet T. G. A.
Audoly, Gilles
Hoepelman, Andy I. M.
Oosterheert, Jan Jelrik
Raoult, Didier
Wever, Peter C.
Dokumenttyp: Artikel
Erscheinungsdatum: 2018
Verlag/Hrsg.: HAL CCSD
Schlagwörter: [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-28747268
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://hal.archives-ouvertes.fr/hal-01791627

International audience ; Non-Hodgkin lymphoma has been linked to infection with Coxiella burnetii, potentially through overproduction of IL-10 during infection with C. burnetii. Description of a case report. We describe a patient with retroperitoneal non-Hodgkin lymphoma and vascular infection with C. burnetii. Immunofluorescence staining and fluorescence in situ hybridization targeting specific C. burnetii 16S rRNA were performed on the retroperitoneal lymphoma tissue sample obtained at diagnosis of NHL. Both were strongly positive for the presence of C. burnetii. This case provokes questions regarding a potential association between C. burnetii and NHL, and underlines the importance of further exploration of this association.