Outcomes for systemic therapy in older patients with metastatic melanoma: Results from the Dutch Melanoma Treatment Registry
Background: The incidence of metastatic melanoma is increasing in all ages. Multiple trials with targeted drugs and immune checkpoint inhibitors showed improved survival in metastatic melanoma. However, patients aged ≥75 years are often under-represented in clinical trials, therefore raising questions on safety and efficacy of treatment. Patients and methods: We analyzed a real-world cohort of 3054 patients with metastatic melanoma stratified for age (≤65 years, 66–74 years and ≥ 75 years), and BRAF status, providing data on treatment strategies, toxicity, and survival. Kaplan Meier curves and... Mehr ...
Verfasser: |
Jochems, Anouk
Bastiaannet, Esther
Aarts, Maureen J. B.
van Akkooi, Alexander C. J.
van den Berkmortel, Franchette W. P. J.
Boers-Sonderen, Marye J.
van den Eertwegh, Alfonsus J. M.
de Glas, Nienke G.
de Groot, Jan Willem B.
Haanen, John B. A. G.
Hospers, Geke A. P.
van der Hoeven, Jacobus J. M.
Piersma, Djura
van Rijn, Rozemarijn S.
Suijkerbuijk, Karijn P. M.
ten Tije, Albert J.
van der Veldt, Astrid A. M.
Vreugdenhil, Gerard
van Zeijl, Michiel C. T.
Kapiteijn, Ellen
Wouters, Michel W. J. M. |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2021 |
Reihe/Periodikum: |
Jochems , A , Bastiaannet , E , Aarts , M J B , van Akkooi , A C J , van den Berkmortel , F W P J , Boers-Sonderen , M J , van den Eertwegh , A J M , de Glas , N G , de Groot , J W B , Haanen , J B A G , Hospers , G A P , van der Hoeven , J J M , Piersma , D , van Rijn , R S , Suijkerbuijk , K P M , ten Tije , A J , van der Veldt , A A M , Vreugdenhil , G , van Zeijl , M C T , Kapiteijn , E & Wouters , M W J M 2021 , ' Outcomes for systemic therapy in older patients with metastatic melanoma: Results from the Dutch Melanoma Treatment Registry ' , Journal of Geriatric Oncology , vol. 12 , no. 7 , pp. 1031-1038 . https://doi.org/10.1016/j.jgo.2021.04.006 |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-28638124 |
Datenquelle: |
BASE;
Originalkatalog |
Powered By: |
BASE |
Link(s) :
|
https://research.vumc.nl/en/publications/832513c7-3e2d-4b85-aa50-f186ea624f87 |