Non-classic EGFR mutations in a cohort of Dutch EGFR-mutated NSCLC patients and outcomes following EGFR-TKI treatment
Background: Data on non-small-cell lung cancer (NSCLC) patients with non-classic epidermal growth factor receptor (EGFR) mutations are scarce, especially in non-Asian populations. The purpose of this study was to evaluate prevalence, clinical characteristics and outcome on EGFR-TKI treatment according to type of EGFR mutation in a Dutch cohort of NSCLC patients. Methods: We retrospectively evaluated a cohort of 240 EGFR-mutated NSCLC patients. Data on demographics, clinical and tumour-related features, EGFR-TKI treatment and clinical outcome were collected and compared between patients with cl... Mehr ...
Verfasser: |
Kuiper, J.L.
Hashemi, S.M.S.
Thunnissen, E.
Snijders, P.J.F.
Grünberg, K.
Bloemena, E.
Sie, D.
Postmus, P.E.
Heideman, D.A.M.
Smit, E.F. |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2016 |
Reihe/Periodikum: |
Kuiper , J L , Hashemi , S M S , Thunnissen , E , Snijders , P J F , Grünberg , K , Bloemena , E , Sie , D , Postmus , P E , Heideman , D A M & Smit , E F 2016 , ' Non-classic EGFR mutations in a cohort of Dutch EGFR-mutated NSCLC patients and outcomes following EGFR-TKI treatment ' , The British journal of cancer , vol. 115 , no. 12 , pp. 1504-1512 . https://doi.org/10.1038/bjc.2016.372 |
Schlagwörter: |
/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
/ name=SDG 3 - Good Health and Well-being |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-28637589 |
Datenquelle: |
BASE;
Originalkatalog |
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Link(s) :
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https://research.vu.nl/en/publications/cb8c6cf6-5cdc-4a2a-a2aa-b71b524f4f36 |