Dutch Parelsnoer Institute-Cerebrovascular Accident (CVA) Study: A Large Multicenter Clinical Biobank with Standardized Collection and Storage

The Dutch Parelsnoer Institute-Cerebrovascular accident (CVA) Study is part of the Parelsnoer Institute (PSI), initiated in 2007 by the Netherlands Federation of University Medical Centers (NFU). PSI is a cooperation of all eight Dutch University Medical Centers (UMCs) and aims at building large prospectively collected datasets with uniformly and standardized storage of biomaterials for complex diseases. Currently, PSI covers 18 disease-specific cohorts called ‘Pearls’, and this number is still growing. One of these cohorts is the Stroke or CVA Pearl. For each of the cohorts, PSI offers the UM... Mehr ...

Verfasser: van Os, H.J.A.
Ruigrok, Y.M.
Manniën, Judith
van Dijk, E.J.
Koudstaal, Peter J.
Luijckx, Gert Jan
Nederkoorn, Paul J.
Oostenbrugge, Robert J.
Visser, M.C.
Kappelle, LJ
Algra, A
Wermer, Marieke J H
Dokumenttyp: Artikel
Erscheinungsdatum: 2018
Schlagwörter: Clinical biobanking / Harmonized standards / Health innovation / International security / Privacy standards / Stroke / Technical and organizational interoperability / Translational medical research / Medicine (miscellaneous) / Biochemistry / Genetics and Molecular Biology (miscellaneous) / Health Informatics / Cell Biology / Health Information Management
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-28629840
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : https://dspace.library.uu.nl/handle/1874/371523

The Dutch Parelsnoer Institute-Cerebrovascular accident (CVA) Study is part of the Parelsnoer Institute (PSI), initiated in 2007 by the Netherlands Federation of University Medical Centers (NFU). PSI is a cooperation of all eight Dutch University Medical Centers (UMCs) and aims at building large prospectively collected datasets with uniformly and standardized storage of biomaterials for complex diseases. Currently, PSI covers 18 disease-specific cohorts called ‘Pearls’, and this number is still growing. One of these cohorts is the Stroke or CVA Pearl. For each of the cohorts, PSI offers the UMCs an infrastructure and standard procedures for storing the specific biomaterials in their certified biobanks. Clinical data are stored in a central database after being pseudonymized to ensure patient privacy. For the Parelsnoer Institute-CVA Study, blood for genetic analysis, serum and plasma are collected according to nationally agreed standards. Currently (November 2017) the Stroke Pearl has stored blood samples with prospectively obtained clinical data of around 6000 patients in all UMCs combined. Blood samples and data are available for all researchers with a methodologically valid research proposal.