Diagnosis and follow-up of MEN1 : Results from the DutchMEN1 study group

Multiple Endocrine Neoplasia type1 (MEN1) is a rare autosomal inherited disorder, characterized by the occurrence of primary hyperparathyroidism (pHPT), duodenopancreatic neuroendocrine tumors (dpNET), and pituitary tumors (PIT). Other tumors associated with MEN1 are lung NET, thymic NET, adrenal adenomas, and even some solid tumors such as breast cancer. MEN1 significantly impacts life-expectancy and quality of life in those affected. On average MEN1 patients have a 27 years decreased life-expectancy. Over recent decades, the follow-up and treatment of MEN1 patients has greatly improved. Stil... Mehr ...