Identification of a novel genomic island associated with vanD-type vancomycin-resistance in six Dutch vancomycin-resistant Enterococcus faecium
Genomic comparison of the first six Dutch vanD-type vancomycin-resistant Enterococcus faecium (VRE) with four vanD-gene clusters from other enterococcal species and anaerobic gut commensals revealed that the vanD-gene cluster was located on a genomic island of variable size. Phylogenetic inferences revealed that the Dutch-VRE were genetically not closely related and genetic variation of the vanD-genomic island was not species specific, which suggest that this island is transferred horizontally between enterococci and anaerobic gut commensals.
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2018 |
Reihe/Periodikum: | Top , J , Sinnige , J C , Brouwer , E C , Werner , G , Corander , J , Severin , J A , Jansen , R , Bathoorn , E , Bonten , M J M , Rossen , J W A & Willems , R J L 2018 , ' Identification of a novel genomic island associated with vanD-type vancomycin-resistance in six Dutch vancomycin-resistant Enterococcus faecium ' , Antimicrobial Agents and Chemotherapy , vol. 62 , no. 3 , e01793-17 . https://doi.org/10.1128/AAC.01793-17 |
Schlagwörter: | Journal Article / CANADA / FLORA / MOLECULAR CHARACTERIZATION / CONJUGATIVE ELEMENTS / GENE-CLUSTER / FAECALIS |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-28619843 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://hdl.handle.net/11370/a8512943-0032-4098-b3e6-5063ac575c1a |