CONTEXT: Nonfunctioning pancreatic neuroendocrine tumors (NF-pNETs) are highly prevalent and constitute an important cause of mortality in patients with multiple endocrine neoplasia type 1 (MEN1). Still, the optimal age to initiate screening for pNETs is under debate. OBJECTIVE: The aim of this work is to assess the age of occurrence of clinically relevant NF-pNETs in young MEN1 patients. METHODS: Pancreatic imaging data of MEN1 patients were retrieved from the DutchMEN Study Group database. Interval-censored survival methods were used to describe age-related penetrance, compare survival curve... Mehr ...
| Verfasser: |
Klein Haneveld, Mirthe J
van Treijen, Mark J C
Pieterman, Carolina R C
Dekkers, Olaf M
van de Ven, Annenienke
de Herder, Wouter W
Zandee, Wouter T
Drent, Madeleine L
Bisschop, Peter H
Havekes, Bas
Vriens, Menno R
Verrijn Stuart, Annemarie A
Valk, Gerlof D
van Leeuwaarde, Rachel S |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2021 |
| Reihe/Periodikum: |
Klein Haneveld , M J , van Treijen , M J C , Pieterman , C R C , Dekkers , O M , van de Ven , A , de Herder , W W , Zandee , W T , Drent , M L , Bisschop , P H , Havekes , B , Vriens , M R , Verrijn Stuart , A A , Valk , G D & van Leeuwaarde , R S 2021 , ' Initiating Pancreatic Neuroendocrine Tumor (pNET) Screening in Young MEN1 Patients : Results From the DutchMEN Study Group ' , Journal of Clinical Endocrinology & Metabolism , vol. 106 , no. 12 , pp. 3515-3525 . https://doi.org/10.1210/clinem/dgab569 |
| Schlagwörter: |
Adolescent
/ Adult
/ Age of Onset
/ Aged
/ Child
/ Preschool
/ Databases
/ Factual
/ Diagnostic Imaging
/ Early Detection of Cancer/methods
/ Female
/ Follow-Up Studies
/ Humans
/ Male
/ Middle Aged
/ Multiple Endocrine Neoplasia Type 1/physiopathology
/ Netherlands/epidemiology
/ Neuroendocrine Tumors/diagnosis
/ Pancreatic Neoplasms/diagnosis
/ Prognosis
/ Retrospective Studies
/ Survival Rate
/ Tumor Burden
/ Young Adult
/ ENDOCRINE NEOPLASIA TYPE-1
/ INTERVAL-CENSORED-DATA
/ surveillance
/ multiple endocrine neoplasia type 1
/ age-related penetrance
/ pancreatic NET |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-28612644 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://cris.maastrichtuniversity.nl/en/publications/b4e76abf-f1e2-4a83-99e7-5808d22c1cdc |
