Results of 2 Years of Treatment with Protease-Inhibitor-Containing Antiretroviral Therapy in Dutch Children Infected with Human Immunodeficiency Virus Type 1
Clinical, virologic, and immunologic responses to treatment that contained either indinavir or nelfinavir (both regimens included zidovudine and lamivudine) were determined in 32 children infected with human immunodeficiency virus type 1 (HIV-1) who participated for ⩾96 weeks in a prospective, open, uncontrolled multicenter trial. The pharmacokinetics of indinavir and of nelfinavir were determined and showed large interindividual differences. After 96 weeks of therapy, 69% and 50% of the patients had an HIV-1 RNA load that was below the HIV assays' detection limits of 500 and 40 copies/mL, res... Mehr ...
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Dokumenttyp: | TEXT |
Erscheinungsdatum: | 2002 |
Verlag/Hrsg.: |
Oxford University Press
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Schlagwörter: | Major Articles |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-28583239 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://cid.oxfordjournals.org/cgi/content/short/34/7/1008 |