[EN] In Belgium, river floods are among the most frequent natural disasters and they may cause important changes on travel demand. In this regard, we propose to set up a large scale scenario using MATSim for guarantying an accurate assessment of the river floods impact on the transportation systems. In terms of inputs, agent-based models require a base year population. In this context, a synthetic population with a respective set of attributes is generated as a key input. Afterwards, agents are assigned activity chains through an activity-based generation process. Finally, the synthetic population and the transportation network are integrated into the dynamic traffic assignment simulator, i.e. MATSim. With respect to data, households travel surveys are the main inputs for synthesizing the populations. Besides, a steady-state inundation map is integrated within MATSim for simulating river floods. To our knowledge, very few studies have focused on how river floods affect transportation systems. In this regard, this research will undoubtedly provide new insights in term of methodology and traffic pattern analysis under disruptions, especially with regard to spatial scale effects. The results indicate that at the municipality level, it is possible to capture the effects of disruptions on travel behavior. In this context, further disaggregation is needed in future studies for identifying to what extent results are sensitive to disaggregation. In addition, results also suggest that the target sub-population exposed to flood risk should be isolated from the rest of the travel demand to reach have more sensitive effects. ; Saadi, I.; Mustafa, A.; Teller, J.; Cools, M. (2016). Calibration of MATSim in the context of natural hazards in Belgium. En XII Congreso de ingeniería del transporte. 7, 8 y 9 de Junio, Valencia (España). Editorial Universitat Politècnica de València. 859-869. https://doi.org/10.4995/CIT2016.2016.4098 ; 859 ; 869