Vitamin D deficiency and hyperparathyroidism in relation to ethnicity: a cross-sectional survey in healthy adults.
BACKGROUND: The study of vitamin D status at population level gained relevance since vitamin D deficiency was recently suggested to trigger chronic disease. AIM OF THE STUDY: We aimed to describe vitamin D status, its association with bone and mineral metabolism and risk factors for deficiency in adults over 40 years in Belgium. METHODS: We conducted a cross-sectional survey in a stratified random sample of 401 subjects aged between 40 and 60 years living in Brussels, and drawn from 4 different ethnic backgrounds: autochthonous Belgian, Moroccan, Turkish and Congolese. 25-Hydroxyvitamin D (25O... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2009 |
Schlagwörter: | Sciences bio-médicales et agricoles / Adult / Belgium -- epidemiology / Belgium -- ethnology / Bone Density / Collagen Type I -- blood / Congo -- ethnology / Cross-Sectional Studies / Female / Health Surveys / Humans / Hyperparathyroidism -- epidemiology / Hyperparathyroidism -- ethnology / Male / Middle Aged / Morocco -- ethnology / Osteocalcin -- blood / Parathyroid Hormone -- blood / Peptides -- blood / Seasons / Sex Factors / Turkey -- ethnology / Vitamin D -- analogs & derivatives / Vitamin D -- blood / Vitamin D Deficiency -- epidemiology / Vitamin D Deficiency -- ethnology / Bone metabolism / Ethnicity / Hyperparathyroidism / Vitamin D / Vitamin D deficiency |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-28538960 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/51774 |
BACKGROUND: The study of vitamin D status at population level gained relevance since vitamin D deficiency was recently suggested to trigger chronic disease. AIM OF THE STUDY: We aimed to describe vitamin D status, its association with bone and mineral metabolism and risk factors for deficiency in adults over 40 years in Belgium. METHODS: We conducted a cross-sectional survey in a stratified random sample of 401 subjects aged between 40 and 60 years living in Brussels, and drawn from 4 different ethnic backgrounds: autochthonous Belgian, Moroccan, Turkish and Congolese. 25-Hydroxyvitamin D (25OHD), parathyroid hormone (PTH), osteocalcin, C-telopeptide and bone mineral density was measured. RESULTS: Three-hundred and six subjects (77%) showed 25OHD concentrations below 50 nmol/l,135 (34%) below 25 nmol/l and 18 (5%) below 12.5 nmol/l. The proportion of subjects with vitamin D deficiency was four times greater amongst those of Moroccan or Turkish descent compared with those of Congolese or Belgian descent. Moroccan subjects showed a significant higher PTH and bone marker concentrations compared to Belgian. Ethnicity, season and sex were independently associated with vitamin D deficiency in multivariate analysis. CONCLUSION: The prevalence of vitamin D deficiency is very high amongst the adult population of Brussels but immigrants are at greater risk. Given the established link between population health and adequate vitamin D status, a policy of vitamin D supplementation should be considered in these risk groups. ; Journal Article ; Research Support, Non-U.S. Gov't ; info:eu-repo/semantics/published