Preoperative chemosensitivity testing as Predictor of Treatment benefit in Adjuvant stage III colon cancer (PePiTA): Protocol of a prospective BGDO (Belgian Group for Digestive Oncology) multicentric study
Background: Surgery is a curative treatment for patients with locally advanced colon cancer, but recurrences are frequent for those with stage III disease. FOLFOX adjuvant chemotherapy has been shown to improve recurrence-free survival and overall survival by more than 20% and is nowadays considered a standard of care. However, the vast majority of patients will not benefit from receiving cytotoxic drugs because they have either already been cured by surgery or because their tumor cells are resistant to the chemotherapy, for which predictive factors are still not available.Identifying which pa... Mehr ...
Verfasser: |
Hendlisz, Alain
Golfinopoulos, Vassilis
Deleporte, Amélie
Paesmans, Marianne
Mansy, Hazem El
Garcia, Camilo
Peeters, Michel
Annemans, Lieven
Vandeputte, Caroline
Maetens, Marion M.
Borbath, Ivan
Dresse, Damien
Houbiers, Ghislain
Fried, Michael
Awada, Ahmad
Piccart-Gebhart, Martine
Van Laethem, Jean-Luc
Flamen, Patrick |
Dokumenttyp: |
Artikel |
Erscheinungsdatum: |
2013 |
Schlagwörter: |
Cancérologie
/ Biologie
/ Adenocarcinoma -- drug therapy -- mortality -- pathology
/ Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
/ Belgium
/ Chemotherapy
/ Adjuvant
/ Colonic Neoplasms -- drug therapy -- mortality -- pathology
/ Fluorouracil -- therapeutic use
/ Follow-Up Studies
/ Gene Rearrangement
/ Humans
/ Leucovorin -- therapeutic use
/ Lymphocytes
/ Tumor-Infiltrating
/ Neoplasm Staging
/ Neoplastic Cells
/ Circulating -- pathology
/ Organoplatinum Compounds -- therapeutic use
/ Polymorphism
/ Single Nucleotide -- genetics
/ Positron-Emission Tomography
/ Preoperative Care
/ Prognosis
/ Prospective Studies
/ Quality of Life
/ Survival Rate
/ Tomography
/ X-Ray Computed
/ Chemosensitivity
/ Colon cancer
/ Early assessment
/ FDG-PET
/ PET/CT |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-28538360 |
Datenquelle: |
BASE;
Originalkatalog |
Powered By: |
BASE |
Link(s) :
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http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/178525 |