Vaccine effectiveness against infection and onwards transmission of COVID-19 : analysis of Belgian contact tracing data, January-June 2021
In Belgium, high-risk contacts of an infected person were offered PCR-testing irrespective of their vacci-nation status. We estimated vaccine effectiveness (VE) against infection and onwards transmission, con-trolling for previous infections, household-exposure and temporal trends. We included 301,741 tests from 25 January to 24 June 2021. Full-schedule vaccination was associated with significant protection against infection. In addition, mRNA-vaccines reduced onward transmission: VE-estimates increased to >90% when index and contact were fully vaccinated. The small number of viral-vector v... Mehr ...
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Dokumenttyp: | journalarticle |
Erscheinungsdatum: | 2021 |
Schlagwörter: | Medicine and Health Sciences / Infectious Diseases / Public Health / Environmental and Occupational Health / General Veterinary / General Immunology and Microbiology / Molecular Medicine |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-28492754 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://biblio.ugent.be/publication/8740414 |
In Belgium, high-risk contacts of an infected person were offered PCR-testing irrespective of their vacci-nation status. We estimated vaccine effectiveness (VE) against infection and onwards transmission, con-trolling for previous infections, household-exposure and temporal trends. We included 301,741 tests from 25 January to 24 June 2021. Full-schedule vaccination was associated with significant protection against infection. In addition, mRNA-vaccines reduced onward transmission: VE-estimates increased to >90% when index and contact were fully vaccinated. The small number of viral-vector vaccines included limited interpretability. (C) 2021 The Author(s). Published by Elsevier Ltd.